4. What are the types of software that you are comfortable with?
This is one of those make-or-break questions that determines hire ability. Based on your response you'll be ratcheted up the interview ladder, or eliminated from further consideration.
The interviewer wants to see if the candidate has placed the company's interests before their own. For example: Has the candidate adequately researched the company to determine how they can help solve a problem, increase profits, or reduce costs? What value-added benefit will this candidate contribute to the organization? Are the candidate's prior achievements indicative of how successful he or she will be in this position?